The Very Best David Sinclair Quotes and Sayings
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About David Sinclair
David Andrew Sinclair AO is an Australian biologist and professor of genetics, for his work on understanding why we age and how to slow its effects. David Sinclair got his Ph.D. in Molecular Genetics at the University of New South Wales, Sydney in 1995.
Dr. Sinclair is co-founder of several biotechnology companies (Sirtris, Ovascience, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others. He is also co-founder and co-chief editor of the journal Aging. His work is featured in five books, two documentary movies, 60 Minutes, Morgan Freeman’s “Through the Wormhole” and other media. ( 1)
In his bestselling book Lifespan: Why We Age — and Why We Don’t Have To, Dr. Sinclair provides an introduction to the new science of aging, as well as providing insights on how we might extend our lifespans right now. ( Get the Audiobook for Free.)
Sinclair believes we’re wasting money and time on what he calls “whack-a-mole” medicine. We’re pursuing cures for individual diseases like cancer, heart disease, and Alzheimer’s, but these don’t get at the real root of the problem: aging.
As Sinclair puts it:
“There is nothing more dangerous to us than age. Yet we have conceded its power over us. And we have turned our fight for better health in other directions.”
Stopping the progression of one disease doesn’t make it any less likely that a person will die of another. While lifespans have increased because of this approach, increases in health span haven’t kept pace.
David Sinclair Quotes
Here are the most powerful quotes by Dr. David Sinclair:
Youth → broken DNA → genome instability → disruption of DNA packaging and gene regulation (the epigenome) → loss of cell identity → cellular senescence → disease → death.
David Sinclair
There isn’t much debate on the downsides of consumption of animal protein. Study after study has demonstrated that heavily animal-based diets are associated with high cardiovascular mortality and cancer risk.
David Sinclair
As a species, we are living much longer than ever. But not much better. Not at all. Over the past century we have gained additional years, but not additional life — not life worth living anyway.
David Sinclair
Why would we choose to focus on problems that impact small groups of people if we could address the problem that impacts everyone — especially if, in doing so, we could significantly impact all those other, smaller problems?
David Sinclair
Thanks to an increasingly sedentary lifestyle and the abundance of sugars and carbohydrates on every supermarket shelf around the globe, high blood sugar is causing the premature deaths of 3.8 million people a year.
David Sinclair
Separating aging from disease obfuscates a truth about how we reach the ends of our lives: though it’s certainly important to know why someone fell from a cliff, it’s equally important to know what brought that person to the precipice in the first place. Aging brings us to the precipice. Give any of us 100 years or so, and it brings us all there.
David Sinclair
a few years ago, researchers noticed a curious phenomenon: people taking metformin were living notably healthier lives — independent, it seemed, of its effect on diabetes.
David Sinclair
We’d die quite quickly without amino acids, the organic compounds that serve as the building blocks for every protein in the human body. Without them — and in particular the nine essential amino acids that our bodies cannot make on their own — our cells can’t assemble the life-giving enzymes needed for life.
David Sinclair
Because as it turns out, exposing your body to less-than-comfortable temperatures is another very effective way to turn on your longevity genes.
David Sinclair
But consider this: though smoking increases the risk of getting cancer fivefold, being 50 years old increases your cancer risk a hundredfold.
David Sinclair
There is great reason for hope on the not-so-distant horizon, but those battling against the ravages of aging right now must do so in a world in which most doctors have never even thought about why we age, let alone how to treat aging.
David Sinclair
As cloning beautifully proves, our cells retain their youthful digital information even when we are old. To become young again, we just need to find some polish to remove the scratches.
David Sinclair
Yes, humans are separated from yeast by a billion years of evolution, but we still have a lot in common. S. cerevisiae shares some 70 percent of our genes.
David Sinclair
In my mind, there are few sins so egregious as extending life without health. This is important. It does not matter if we can extend lifespans if we cannot extend healthspans to an equal extent. And so if we’re going to do the former, we have an absolute moral obligation to do the latter.
David Sinclair
We can’t prevent all DNA damage — and we wouldn’t want to because it’s essential for the function of the immune system and even for consolidating our memories57 — but we do want to prevent extra damage. And there’s a lot of extra damage to be had out there.
David Sinclair
take 1 gram (1,000 mg) of NMN every morning, along with 1 gram of resveratrol (shaken into my homemade yogurt) and 1 gram of metformin.7 • I take a daily dose of vitamin D, vitamin K2, and 83 mg of aspirin.
David Sinclair
Broadly speaking, the more often a cause shows up on a death certificate, the more attention society gives to fighting it. This is why heart disease, type 2 diabetes, and dementia are major focuses of research and interventionary medical care, while aging is not, even though aging is the greatest cause of all those diseases.
David Sinclair
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Originally published at https://motiveex.com on May 29, 2020.
